Differentiation of the tumor microenvironment: are CAFs the Organizer?
Sign Up to like & getrecommendations! Published in 2021 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2021.11.008
Abstract: Cancers contain a suite of genetically stable cells within an extracellular matrix, collectively termed the tumor microenvironment (TME). The TME strongly influences disease outcome for patients. Gleaning clues from the literature, we propose that the… read more here.
Keywords: differentiation tumor; differentiation; organizer; tumor microenvironment ... See more keywords
Abstract 1595: Thyroid hormone drives the terminal differentiation of tumor cells in medulloblastoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-1595
Abstract: Hypothyroidism is commonly detected in patients with medulloblastoma (MB), a pediatric brain tumor, which is generally considered as a treatment-related complication. Although reduced levels of thyroid hormone (TH) significantly correlate with poor survival of patients… read more here.
Keywords: differentiation tumor; tumor cells; thyroid hormone; differentiation ... See more keywords