mTORC1 Inhibits NF‐κB/NFATc1 Signaling and Prevents Osteoclast Precursor Differentiation, In Vitro and In Mice
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3172
Abstract: The mechanistic target of rapamycin complex 1 (mTORC1) is a critical sensor for bone homeostasis and bone formation; however, the role of mTORC1 in osteoclast development and the underlying mechanisms have not yet been fully… read more here.
Keywords: mtorc1 osteoclast; mtorc1; bone; differentiation vitro ... See more keywords
Adipogenic and Osteogenic Differentiation of In Vitro Aged Human Mesenchymal Stem Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/7651_2018_197
Abstract: Multipotent mesenchymal stem cells (MSCs) are an attractive candidate for regeneration of damaged cells, tissues, and organs. Due to limited availabilities, MSC populations must be rapidly expanded to satisfy clinical needs. However, senescence attributed to… read more here.
Keywords: adipogenic osteogenic; osteogenic differentiation; differentiation vitro; vitro ... See more keywords
Periplaneta Americana extract inhibits osteoclastic differentiation in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Cell Proliferation"
DOI: 10.1111/cpr.13341
Abstract: Periplaneta americana extract (PAE) is proven to be promising in treating fever, wound healing, liver fibrosis, and cardiovascular disease. However, the role of PAE in skeletal disorders remains unclear. This study investigated whether PAE regulates… read more here.
Keywords: osteoclastic differentiation; americana extract; differentiation vitro; periplaneta americana ... See more keywords