Withholding Proton Pump Inhibitors to Prevent Recurrent Clostridium difficile: Time for a Randomized Trial.
Sign Up to like & getrecommendations! Published in 2017 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2017.0233
Abstract: Clostridium difficile causes almost half a million infections annually among hospitalized and community-dwelling patients in the United States, and approximately 1 in 5 patients will develop arecurrentCdifficile infection.1 Therefore, identificationofmodifiable risk factors for incident and… read more here.
Keywords: medicine; difficile; infection; acid suppressants ... See more keywords
2,4‐Disubstituted 5‐Nitroimidazoles Potent against Clostridium difficile
Sign Up to like & getrecommendations! Published in 2019 at "ChemMedChem"
DOI: 10.1002/cmdc.201800784
Abstract: Metronidazole is one of the first‐line treatments for non‐severe Clostridium difficile infections (CDI). However, resistance limits its use in cases of severe and complicated CDI. Structure–activity relationships previously described for the 5‐nitroimidazole series have shown… read more here.
Keywords: clostridium difficile; difficile; nitroimidazoles potent; potent clostridium ... See more keywords
Clostridium difficile, the Difficult “Kloster” Fuelled by Antibiotics
Sign Up to like & getrecommendations! Published in 2018 at "Current Microbiology"
DOI: 10.1007/s00284-018-1543-8
Abstract: Clostridium difficile is normally present in low numbers in a healthy adult gastro-intestinal tract (GIT). Drastic changes in the microbial population, e.g., dysbiosis caused by extensive treatment with antibiotics, stimulates the growth of resistant strains… read more here.
Keywords: clostridium difficile; difficult kloster; difficile; difficile difficult ... See more keywords
Prevalence of Clostridium difficile isolated from various raw meats in Korea
Sign Up to like & getrecommendations! Published in 2018 at "Food Science and Biotechnology"
DOI: 10.1007/s10068-018-0318-0
Abstract: Clostridium difficile is an anaerobic, toxin-producing pathogen that causes human infection possibly through the consumption of meat. Clostridium difficile was isolated from 45 of 415 (10.8%) various raw meat samples collected in nationwide markets in… read more here.
Keywords: difficile isolated; clostridium difficile; difficile; raw meats ... See more keywords
A comparison of air sampling methods for Clostridium difficile endospore aerosol
Sign Up to like & getrecommendations! Published in 2019 at "Aerobiologia"
DOI: 10.1007/s10453-019-09566-2
Abstract: The airborne dissemination of Clostridium difficile (C. difficile) endospores (spores) in healthcare environments is documented in multiple studies. Once airborne, spores have the potential for transport on air currents to other areas. This study compared… read more here.
Keywords: clostridium difficile; airborne spores; sampling methods; difficile ... See more keywords
Reducing Cost and Complexity of Fecal Microbiota Transplantation Using Universal Donors for Recurrent Clostridium difficile Infection
Sign Up to like & getrecommendations! Published in 2019 at "Advances in Therapy"
DOI: 10.1007/s12325-019-00974-x
Abstract: IntroductionFecal microbiota transplantation resolves recurrent Clostridium difficile infections in greater than 82% of patients. Highly screened, processed universal donor fecal material is available. We compared cost and scheduling efficiency of fecal microbiota transplantation by universal… read more here.
Keywords: difficile; microbiota; microbiota transplantation; fecal microbiota ... See more keywords
Community-acquired fulminant colitis caused by binary toxin-producing Clostridium difficile in Japan
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Journal of Gastroenterology"
DOI: 10.1007/s12328-019-00949-z
Abstract: We report a case of community-acquired fulminant colitis caused by Clostridium difficile in Japan. A 46-year-old woman was diagnosed with severe infectious enterocolitis and was admitted at another hospital. The stool culture was positive for… read more here.
Keywords: binary toxin; acquired fulminant; difficile; community acquired ... See more keywords
Washer disinfector and alkaline detergent efficacy against C. difficile on plastic bedpans.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of infection control"
DOI: 10.1016/j.ajic.2019.11.028
Abstract: BACKGROUND Clostridioides difficile is a major cause of infectious antibiotic resistant diarrhea. C. difficile spores are shed in patient stool, are hearty and difficult to kill. Bedpans are often used by patients with C. difficile… read more here.
Keywords: difficile; kill; efficacy; washer disinfector ... See more keywords
Low prevalence of Clostridium difficile colonization in patients in long-term care facilities in Graz, Austria: A point-prevalence study.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of infection control"
DOI: 10.1016/j.ajic.2019.12.011
Abstract: BACKGROUND We aimed to determine the prevalence of asymptomatic colonization by C. difficile in stool of residents in four long-term care facilities (LTCFs) in Graz, Austria and to identify factors associated with colonization. METHODS We… read more here.
Keywords: difficile; graz austria; long term; study ... See more keywords
Three-centre evaluation of laboratory Clostridium difficile detection algorithms and the EntericBio® realtime C. difficile assay.
Sign Up to like & getrecommendations! Published in 2018 at "Anaerobe"
DOI: 10.1016/j.anaerobe.2017.12.006
Abstract: The comparatively high cost of laboratory detection methods for Clostridium difficile infection (CDI) coupled to a low prevalence rate has resulted in testing algorithms that use cheaper and relatively sensitive screening methods, followed by more… read more here.
Keywords: clostridium difficile; detection; entericbio realtime; difficile ... See more keywords
Binary Clostridium difficile toxin (CDT) - A virulence factor disturbing the cytoskeleton.
Sign Up to like & getrecommendations! Published in 2018 at "Anaerobe"
DOI: 10.1016/j.anaerobe.2018.03.001
Abstract: Clostridium difficile infection causes antibiotics-associated diarrhea and pseudomembranous colitis. Major virulence factors of C. difficile are the Rho-glucosylating toxins TcdA and TcdB. In addition, many, so-called hypervirulent C. difficile strains produce the binary actin-ADP-ribosylating toxin CDT. CDT… read more here.
Keywords: cytoskeleton; clostridium difficile; difficile; cdt ... See more keywords