Identification of thioredoxin domain containing family members' expression pattern and prognostic value in diffuse gliomas via in silico analysis
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5169
Abstract: Gliomas are the most prevalent primary tumors of the central nervous system. Their aggressive nature and the obstacles arising during therapy highlights the importance of finding new prognostic markers and therapy targets for gliomas. TXNDC… read more here.
Keywords: family members; gliomas; identification thioredoxin; diffuse gliomas ... See more keywords
Identification of IDH and TERTp mutation status using 1H‐MRS in 112 hemispheric diffuse gliomas
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.26964
Abstract: There is a growing interest in noninvasively defining molecular subsets of hemispheric diffuse gliomas based on the isocitrate dehydrogenase (IDH) and telomerase reverse transcriptase gene promoter (TERTp) mutation status, which correspond to distinct tumor entities,… read more here.
Keywords: mutation status; hemispheric diffuse; tertp mutation; diffuse gliomas ... See more keywords
Diagnostic implications of TERT promoter mutation status in diffuse gliomas in a routine clinical setting
Sign Up to like & getrecommendations! Published in 2017 at "Virchows Archiv"
DOI: 10.1007/s00428-017-2216-x
Abstract: IDH (isocitrate dehydrogenase) gene mutations are present in most diffuse low-grade gliomas and define the clinico-pathological core of the respective morphologically defined entities. Conversely, according to the 2016 WHO classification, the majority of glioblastomas belong… read more here.
Keywords: promoter mutation; tert promoter; diffuse gliomas; idh wildtype ... See more keywords
Features of diffuse gliomas that are misdiagnosed on initial neuroimaging: a case control study
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-018-2939-9
Abstract: PurposeThe neuroimaging diagnosis of diffuse gliomas can be challenging owing to their variable clinical and radiologic presentation. The purpose of this study was to identify factors that are associated with imaging errors in the diagnosis… read more here.
Keywords: initial neuroimaging; case control; study; diffuse gliomas ... See more keywords
Histopathological grading affects survival in patients with IDH-mutant grade II and grade III diffuse gliomas.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of cancer"
DOI: 10.1016/j.ejca.2020.06.018
Abstract: BACKGROUND Diffuse grade II and grade III gliomas are actually classified in accordance with the presence of isocitrate dehydrogenase mutation (IDH-mut) and the deletion of both 1p and 19q chromosome arms (1p/19q codel). The role… read more here.
Keywords: grade iii; grade grade; diffuse gliomas; grade ... See more keywords
Diffuse gliomas exhibit whole brain impaired cerebrovascular reactivity.
Sign Up to like & getrecommendations! Published in 2018 at "Magnetic resonance imaging"
DOI: 10.1016/j.mri.2017.09.017
Abstract: PURPOSE Cerebral diffuse gliomas exhibit perilesional impaired cerebrovascular reactivity (CVR), yet the degree of impairment as well as its full spatial extent in the brain remains unknown. With quantitative fMRI, we studied twelve subjects with… read more here.
Keywords: exhibit; diffuse gliomas; cvr; brain ... See more keywords
PD-1 related transcriptome profile and clinical outcome in diffuse gliomas
Sign Up to like & getrecommendations! Published in 2018 at "OncoImmunology"
DOI: 10.1080/2162402x.2017.1382792
Abstract: ABSTRACT Background: PD-1 plays a critical part in control of immune response to malignancy. Anti-PD-1 treatment is a hopeful strategy to improve the dismal prognosis of gliomas. To characterize the role of PD-1 in diffuse… read more here.
Keywords: gliomas; analysis; diffuse gliomas; transcriptome profile ... See more keywords
Molecular marker testing and reporting completeness for adult-type diffuse gliomas in the United States.
Sign Up to like & getrecommendations! Published in 2022 at "Neuro-oncology practice"
DOI: 10.1093/nop/npac079
Abstract: Background A newly developed brain molecular marker (BMM) data item was implemented by US cancer registries for individuals diagnosed with brain tumors in 2018-including IDH and 1p/19q-co-deletion statuses for adult-type diffuse gliomas. We thus investigated… read more here.
Keywords: diffuse gliomas; testing reporting; reporting completeness; adult type ... See more keywords
Characterization of Diffuse Gliomas With Histone H3-G34 Mutation by MRI and Dynamic 18F-FET PET
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Nuclear Medicine"
DOI: 10.1097/rlu.0000000000002300
Abstract: Background Recent data suggest that diffuse gliomas carrying mutations in codon 34 of the H3 histone family 3A protein represent a very rare, distinct subgroup of IDH–wild type malignant astrocytic gliomas. However, characteristics detectable by… read more here.
Keywords: fet pet; 18f fet; diffuse gliomas;
Diffuse gliomas with FGFR3‐TACC3 fusion have characteristic histopathological and molecular features
Sign Up to like & getrecommendations! Published in 2018 at "Brain Pathology"
DOI: 10.1111/bpa.12563
Abstract: Adult glioblastomas, IDH‐wildtype represent a heterogeneous group of diseases. They are resistant to conventional treatment by concomitant radiochemotherapy and carry a dismal prognosis. The discovery of oncogenic gene fusions in these tumors has led to… read more here.
Keywords: fgfr3 tacc3; tacc3 fusion; diffuse gliomas; molecular features ... See more keywords
Classification of adult‐type diffuse gliomas: Impact of the World Health Organization 2021 update
Sign Up to like & getrecommendations! Published in 2022 at "Brain Pathology"
DOI: 10.1111/bpa.13062
Abstract: Over the last decade, developments in molecular profiling have radically altered the diagnosis, classification, and management of numerous cancer types, with primary brain tumors being no exception. Although historically brain tumors have been classified based… read more here.
Keywords: diffuse gliomas; classification; adult type; brain ... See more keywords