Topical delivery of PD‐1 inhibitors with laser‐assisted passive diffusion and active intradermal injection: Investigation of cutaneous pharmacokinetics and biodistribution patterns
Sign Up to like & getrecommendations! Published in 2021 at "Lasers in Surgery and Medicine"
DOI: 10.1002/lsm.23504
Abstract: Current cancer immunotherapeutic treatment with PD‐1 inhibitors is administered systemically. However, a local treatment strategy may be advantageous as it could provide targeted drug delivery as well as attenuate side effects seen with systemic treatments.… read more here.
Keywords: cutaneous pharmacokinetics; pharmacokinetics biodistribution; diffusion active; assisted passive ... See more keywords
Diffusion of active dimers in a Couette flow.
Sign Up to like & getrecommendations! Published in 2017 at "Soft matter"
DOI: 10.1039/c7sm00356k
Abstract: We study the 3D dynamics of an elastic dimer consisting of an active swimmer bound to a passive cargo, both suspended in a Couette flow. Using numerical simulations, we determine the diffusivity of such an… read more here.
Keywords: active dimers; diffusion active; couette flow; dimer ... See more keywords
Diffusion of active particles in convective flows.
Sign Up to like & getrecommendations! Published in 2021 at "Soft matter"
DOI: 10.1039/d0sm01784a
Abstract: We numerically investigated the diffusion of an active Janus particle in periodic arrays of planar counter-rotating convection rolls at high Péclet numbers. We considered convection patterns with distinct longitudinal and transverse advection properties and characterized… read more here.
Keywords: diffusion active; active particles; diffusion; convective flows ... See more keywords
Boundary design regulates the diffusion of active matter in heterogeneous environments.
Sign Up to like & getrecommendations! Published in 2023 at "Soft matter"
DOI: 10.1039/d2sm01421a
Abstract: Physical boundaries play a key role in governing the overall transport properties of nearby self-propelled particles. In this work, we develop dispersion theories and conduct Brownian dynamics simulations to predict the coupling between surface accumulation… read more here.
Keywords: matter; design regulates; diffusion active; transport ... See more keywords
Tracer diffusion in active suspensions.
Sign Up to like & getrecommendations! Published in 2017 at "Physical Review E"
DOI: 10.1103/physreve.95.052605
Abstract: We study the diffusion of a Brownian probe particle of size R in a dilute dispersion of active Brownian particles of size a, characteristic swim speed U_{0}, reorientation time τ_{R}, and mechanical energy k_{s}T_{s}=ζ_{a}U_{0}^{2}τ_{R}/6, where… read more here.
Keywords: diffusion active; diffusion; probe; energy ... See more keywords