Slower diffusion and anomalous association of R453W lamin A protein alter nuclear architecture in AD-EDMD
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DOI: 10.1039/d2ra05620h
Abstract: Lamins maintain the shape and rigidity of the nucleus in the form of a proteinaceous scaffold underneath the inner nuclear membrane (INM) and provide anchorage to chromatin and other nuclear proteins. Mutations in the human… read more here.
Keywords: association r453w; fold domain; anomalous association; diffusion anomalous ... See more keywords