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Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0202201
Abstract: Objective Interpretation of diffusion MRI in the living brain requires validation against gold standard histological measures. We compared diffusion values of the nigrostriatal tract to PET and histological results in non-human primates (NHPs) with varying…
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Keywords:
diffusion;
nigrostriatal tract;
diffusion measures;
fiber density ... See more keywords
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Published in 2022 at "Journal of Parkinson's Disease"
DOI: 10.3233/jpd-223349
Abstract: Background: MRI is a valuable method to assist in the diagnostic work-up of Parkinson’s disease (PD). The olfactory tract (OT) has been proposed as a potential MRI biomarker for distinguishing PD patients from healthy controls.…
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Keywords:
diffusion;
early stage;
diffusion measures;
healthy controls ... See more keywords
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Published in 2023 at "Brain Sciences"
DOI: 10.3390/brainsci13030391
Abstract: The pathology of Parkinson’s disease (PD) involves the death of dopaminergic neurons in the substantia nigra (SN), which slowly influences downstream basal ganglia pathways as dopamine transport diminishes. Diffusion magnetic resonance imaging (MRI) has been…
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Keywords:
diffusion;
diffusion measures;
values found;
mri ... See more keywords