Target protein identification in live cells and organisms with a non-diffusive proximity tagging system
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DOI: 10.7554/elife.102667
Abstract: Identifying target proteins for bioactive molecules is essential for understanding their mechanisms, developing improved derivatives, and minimizing off-target effects. Despite advances in target identification (target-ID) technologies, significant challenges remain, impeding drug development. Most target-ID methods… read more here.
Keywords: tagging system; system; diffusive proximity; target ... See more keywords