Enantioselective Formation of All-Carbon Quaternary Stereocenters in gem-Difluorinated Cyclopropanes via Rhodium-Catalyzed Stereoablative Kinetic Resolution.
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DOI: 10.1021/acs.orglett.2c02410
Abstract: Herein, we report an effective method to offer chiral gem-difluorinated cyclopropanes containing an all-carbon quaternary stereocenter by rhodium-catalyzed stereoablative kinetic resolution. The activation of a sterically hindered all-carbon quaternary C-C bond through oxidative addition with… read more here.
Keywords: rhodium catalyzed; gem difluorinated; difluorinated cyclopropanes; carbon quaternary ... See more keywords