Controllable catalytic difluorocarbene transfer enables access to diversified fluoroalkylated arenes
Sign Up to like & getrecommendations! Published in 2019 at "Nature Chemistry"
DOI: 10.1038/s41557-019-0331-9
Abstract: Difluorocarbene has important applications in pharmaceuticals, agrochemicals and materials, but all these applications proceed using just a few types of reaction by taking advantage of its intrinsic electrophilicity. Here, we report a palladium-catalysed strategy that… read more here.
Keywords: difluorocarbene; catalytic difluorocarbene; difluorocarbene transfer; controllable catalytic ... See more keywords
Difluorocarbene transfer from a cobalt complex to an electron-deficient alkene.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc01418j
Abstract: We report the synthesis of the trifluoromethyl cobalt(iii)tetraphenylporphyrinato complex [Co(TPP)CF3], which loses fluoride upon one-electron reduction and transfers a difluorocarbene moiety to n-butyl acrylate to produce the corresponding gem-difluorocyclopropane. Catalytic CF2 transfer from Me3SiCF3 to… read more here.
Keywords: cobalt complex; cobalt; difluorocarbene transfer; transfer cobalt ... See more keywords