[3+2] Cycloaddition reactions of β-diazo-α,α-difluoromethylphosphonates with α,β-unsaturated esters
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DOI: 10.1016/j.jfluchem.2021.109899
Abstract: Abstract (β-diazo-α,α-difluoroethyl)phosphonates as an analog of difluoro diazoethane has been designed as a powerful tool for the assembly of α,α-difluorinated phosphonate-containing molecules. Here, we report a [3+2] dipolar cycloaddition reaction of in situ generated (β-diazo-α,α-difluoroethyl)phosphonates… read more here.
Keywords: diazo difluoromethylphosphonates; difluoromethylphosphonates unsaturated; unsaturated esters; cycloaddition reactions ... See more keywords
Design of (β-diazo-α,α-difluoroethyl)phosphonates and their application as masked carbenes in visible light-promoted coupling reactions with sulfonic acids
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DOI: 10.1039/d0qo01394c
Abstract: We elaborate a method for the generation of (2-diazo-1,1-difluoroethyl)phosphonates from (β-amino-α,α-difluoroethyl)phosphonates as precursors and their application as masked carbenes in coupling reactions with sulfonic acids under photochemical conditions. Varieties of coupling partners including aminophosphonates and… read more here.
Keywords: application masked; masked carbenes; sulfonic acids; diazo difluoroethyl ... See more keywords