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Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.130472
Abstract: Abstract A convenient synthesis of 2-(2-(difluoromethoxy)aryl)benzo[d]thiazoles from 2- (o-hydroxyaryl)benzothiazoles and commercially available ethyl difluoroiodoacetate (ICF2CO2Et) is described. The transformation was amenable to a one-pot, sequential three-component protocol from o-hydroxybenzaldehyde, o-aminothiophenol, and ICF2CO2Et promoted by KOH.…
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Keywords:
synthesis;
aryl benzo;
difluoromethoxy aryl;
one pot ... See more keywords