A Novel DNA-Platinum Nanoparticle Conjugation Method for Attomolar Detection and Quantitation of Nucleic Acids Using the Microbubbling Digital Assay.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.4c05958
Abstract: Platinum nanoparticles (PtNPs) hold promise for developing novel point-of-care diagnostic tools. This study focuses on the synthesis of single-stranded DNA-platinum nanoparticle (DNA-PtNP) conjugates used as detection probes for nucleic acids in an ultrasensitive and amplification-free… read more here.
Keywords: microbubbling digital; conjugation; digital assay; dna ... See more keywords
An Amplification-Free Digital Assay Based on Primer Exchange Reaction-Mediated Botryoidal-Like Fluorescent Polystyrene Dots to Detect Multiple Pathogenic Bacteria.
Sign Up to like & getrecommendations! Published in 2024 at "ACS nano"
DOI: 10.1021/acsnano.4c09069
Abstract: Multiple and ultrasensitive detection of pathogenic bacteria is critical but remains a challenge. Here, we introduce a digital assay for multiplexed and target DNA amplification-free detection of pathogenic bacteria using botryoidal-like fluorescent polystyrene dots (PS-dots),… read more here.
Keywords: reaction; amplification free; botryoidal like; digital assay ... See more keywords