Digital microfluidic immobilized cytochrome P450 reactors with integrated inkjet-printed microheaters for droplet-based drug metabolism research
Sign Up to like & getrecommendations! Published in 2018 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-1280-7
Abstract: We report the development and characterization of digital microfluidic (DMF) immobilized enzyme reactors (IMERs) for studying cytochrome P450 (CYP)-mediated drug metabolism on droplet scale. The on-chip IMERs consist of porous polymer (thiol-ene) monolith plugs prepared… read more here.
Keywords: inkjet printed; droplet based; digital microfluidic; printed microheaters ... See more keywords
Sample preparation of chemical warfare agent simulants on a digital microfluidic (DMF) device using magnetic bead-based solid-phase extraction
Sign Up to like & getrecommendations! Published in 2017 at "Microfluidics and Nanofluidics"
DOI: 10.1007/s10404-017-1976-6
Abstract: In the present study, the purification and extraction of five chemical warfare agent (CWA) simulants, dimethyl methyl phosphonate, di(propylene glycol) methyl ether, methyl salicylate, triethyl phosphate, and diethyl phthalate, on a digital microfluidic (DMF) device… read more here.
Keywords: extraction; warfare agent; digital microfluidic; chemical warfare ... See more keywords
Driving and sorting of the fluorescent droplets on digital microfluidic platform
Sign Up to like & getrecommendations! Published in 2018 at "Microfluidics and Nanofluidics"
DOI: 10.1007/s10404-018-2154-1
Abstract: In this paper, we present a digital microfluidic droplet sorting platform to achieve automated droplet sorting based on fluorescent detection. We design and fabricate a kind of digital microfluidic chip for manipulating nano-liter-sized liquid droplets,… read more here.
Keywords: droplet; sorting fluorescent; driving sorting; digital microfluidic ... See more keywords
Electrowetting Behavior and Digital Microfluidic Applications of Fluorescent, Polymer-Encapsulated Quantum Dot Nanofluids.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b07983
Abstract: Digital microfluidics is a liquid handling technology capable of rapidly and autonomously controlling multiple discrete droplets across an array of electrodes, and has seen continual growth in the fields of chemistry, biology, and optics. This… read more here.
Keywords: dot nanofluids; electrowetting behavior; quantum dot; behavior digital ... See more keywords
Efficient and Adaptive Error Recovery in a Micro-Electrode-Dot-Array Digital Microfluidic Biochip
Sign Up to like & getrecommendations! Published in 2018 at "IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems"
DOI: 10.1109/tcad.2017.2729347
Abstract: A digital microfluidic biochip (DMFB) is an attractive technology platform for automating laboratory procedures in biochemistry. In recent years, DMFBs based on a micro-electrode-dot-array (MEDA) architecture have been proposed. MEDA biochips can provide advantages of… read more here.
Keywords: recovery; error recovery; digital microfluidic; microfluidic biochip ... See more keywords
Integrated Control-Fluidic Codesign Methodology for Paper-Based Digital Microfluidic Biochips
Sign Up to like & getrecommendations! Published in 2020 at "IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems"
DOI: 10.1109/tcad.2019.2894820
Abstract: Paper-based digital microfluidic biochips (P-DMFBs) have recently emerged as a promising low-cost and fast-responsive platform for biochemical assays. In P-DMFBs, electrodes and control lines are printed on a piece of photograph paper using an inkjet… read more here.
Keywords: methodology; control; paper; design ... See more keywords
Bio-Protocol Watermarking on Digital Microfluidic Biochips
Sign Up to like & getrecommendations! Published in 2019 at "IEEE Transactions on Information Forensics and Security"
DOI: 10.1109/tifs.2019.2907185
Abstract: Advancements in digital microfluidic biochip (DMFB) technologies are paving the way for low-cost and automated platforms for implementing bio-protocols. However, the deployment of DMFBs outside of controlled settings will make them vulnerable to intellectual property… read more here.
Keywords: watermarking digital; bio protocol; protocol watermarking; protocol ... See more keywords
Droplet Handling for Chemical Reactors Using a Digital Microfluidic Device
Sign Up to like & getrecommendations! Published in 2020 at "Chemistry Letters"
DOI: 10.1246/cl.200654
Abstract: We present droplet manipulation using a digital microfluidic device comprising downward electrodes. Using this device, we demonstrated droplet transportation, programmable dispensing, and droplet c... read more here.
Keywords: digital microfluidic; droplet handling; using digital; microfluidic device ... See more keywords
PortaDrop: A portable digital microfluidic platform providing versatile opportunities for Lab-On-A-Chip applications
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0238581
Abstract: Electrowetting-on-dielectric is a decent technique to manipulate discrete volumes of liquid in form of droplets. In the last decade, electrowetting-on-dielectric systems, also called digital microfluidic systems, became more frequently used for a variety of applications… read more here.
Keywords: digital microfluidic; portadrop portable; portable digital; spectroscopy ... See more keywords
A Digital Microfluidic Device Integrated with Electrochemical Impedance Spectroscopy for Cell-Based Immunoassay
Sign Up to like & getrecommendations! Published in 2022 at "Biosensors"
DOI: 10.3390/bios12050330
Abstract: The dynamic immune response to various diseases and therapies has been considered a promising indicator of disease status and therapeutic effectiveness. For instance, the human peripheral blood mononuclear cell (PBMC), as a major player in… read more here.
Keywords: system; cell; spectroscopy; electrochemical impedance ... See more keywords
Bead Number Effect in a Magnetic-Beads-Based Digital Microfluidic Immunoassay
Sign Up to like & getrecommendations! Published in 2022 at "Biosensors"
DOI: 10.3390/bios12050340
Abstract: In a biomedical diagnosis with a limited sample volume and low concentration, droplet-based microfluidics, also called digital microfluidics, becomes a very attractive approach. Previously, our group developed a magnetic-beads-based digital microfluidic immunoassay with a bead… read more here.
Keywords: number; magnetic beads; based digital; microfluidic immunoassay ... See more keywords