Fluid Mixing for Low-Power 'Digital Microfluidics' Using Electroactive Molecular Monolayers.
Sign Up to like & getrecommendations! Published in 2018 at "Small"
DOI: 10.1002/smll.201703344
Abstract: A switchable electrode, which relies on an indium-tin oxide conductive substrate coated with a self-assembled monolayer terminated with an anthraquinone group (AQ), is reported as an electrowetting system. AQ electrochemical features confer the capability of… read more here.
Keywords: microfluidics using; power digital; mixing low; digital microfluidics ... See more keywords
Integrating DNA Encapsulates and Digital Microfluidics for Automated Data Storage in DNA.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202107381
Abstract: Using DNA as a durable, high-density storage medium with eternal format relevance can address a future data storage deficiency. The proposed storage format incorporates dehydrated particle spots on glass, at a theoretical capacity of more… read more here.
Keywords: dna; storage; dna encapsulates; integrating dna ... See more keywords
Piezo-driven acoustic streaming in an electrowetting-on-dielectric digital microfluidics device
Sign Up to like & getrecommendations! Published in 2017 at "Microfluidics and Nanofluidics"
DOI: 10.1007/s10404-017-2012-6
Abstract: We report the integration of a lead zirconate titanate, $$\hbox {Pb[Zr}_{x}\hbox {Ti}_{1-x}\hbox {O}_{3}$$Pb[ZrxTi1-xO3] (PZT), piezoelectric transducer disk into the top plate of an otherwise conventional electrowetting-on-dielectric (EWD) digital microfluidics device to demonstrate on-demand induction of… read more here.
Keywords: electrowetting dielectric; piezo driven; hbox; digital microfluidics ... See more keywords
Digital Microfluidics-Enabled Analysis of Individual Variation in Liver Cytochrome P450 Activity.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c03258
Abstract: The superfamily of hepatic cytochrome P450 (CYP) enzymes is responsible for the intrinsic clearance of the majority of therapeutic drugs in humans. However, the kinetics of drug clearance via CYPs varies significantly among individuals due… read more here.
Keywords: liver; digital microfluidics; cytochrome p450; activity ... See more keywords
Surface-Enhanced Raman Spectroscopic Probing in Digital Microfluidics through a Microspray Hole.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c04053
Abstract: We report a novel approach for surface-enhanced Raman spectroscopy (SERS) detection in digital microfluidics (DMF). This is made possible by a microspray hole (μSH) that uses an electrostatic spray (ESTAS) for sample transfer from inside… read more here.
Keywords: surface enhanced; microspray hole; enhanced raman; digital microfluidics ... See more keywords
Integrated Digital Microfluidics NMR Spectroscopy: A Key Step toward Automated In Vivo Metabolomics.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c04201
Abstract: Toxicity testing is currently undergoing a paradigm shift from examining apical end points such as death, to monitoring sub-lethal toxicity in vivo. In vivo nuclear magnetic resonance (NMR) spectroscopy is a key platform in this… read more here.
Keywords: integrated digital; vivo; spectroscopy; spectroscopy key ... See more keywords
"Plug-n-Play" Sensing with Digital Microfluidics.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b05375
Abstract: Digital microfluidics (DMF) is a platform that enables highly reconfigurable and automated fluidic operations using a generic device architecture. A unique hallmark of DMF is its "flexibility": a generic device design can be used and… read more here.
Keywords: dmf; pnp dmf; digital microfluidics; plug play ... See more keywords
Antifouling Properties of Pluronic and Tetronic Surfactants in Digital Microfluidics.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c17317
Abstract: Fouling at liquid-solid interfaces is a pernicious problem for a wide range of applications, including those that are implemented by digital microfluidics (DMF). There are several strategies that have been used to combat surface fouling… read more here.
Keywords: tetronic additives; microscopy; pluronic tetronic; antifouling properties ... See more keywords
On-the-Fly Mass Spectrometry in Digital Microfluidics Enabled by a Microspray Hole: Toward Multidimensional Reaction Monitoring in Automated Synthesis Platforms.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c01651
Abstract: We report an approach for the online coupling of digital microfluidics (DMF) with mass spectrometry (MS) using a chip-integrated microspray hole (μSH). The technique uses an adapted electrostatic spray ionization (ESTASI) method to spray a… read more here.
Keywords: mass spectrometry; synthesis; microspray hole; chip ... See more keywords
Role of Digital Microfluidics in Enabling Access to Laboratory Automation and Making Biology Programmable
Sign Up to like & getrecommendations! Published in 2020 at "SLAS Technology"
DOI: 10.1177/2472630320931794
Abstract: Digital microfluidics (DMF) is a liquid handling technique that has been demonstrated to automate biological experimentation in a low-cost, rapid, and programmable manner. This review discusses the role of DMF as a “digital bioconverter”—a tool… read more here.
Keywords: role digital; microfluidics enabling; dmf; biology ... See more keywords
Digital Microfluidics-Powered Real-Time Monitoring of Isothermal DNA Amplification of Cancer Biomarker
Sign Up to like & getrecommendations! Published in 2022 at "Biosensors"
DOI: 10.3390/bios12040201
Abstract: We introduce a digital microfluidics (DMF) platform specifically designed to perform a loop-mediated isothermal amplification (LAMP) of DNA and applied it to a real-time amplification to monitor a cancer biomarker, c-Myc (associated to 40% of… read more here.
Keywords: amplification; cancer biomarker; real time; digital microfluidics ... See more keywords