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Published in 2021 at "Clinical Rheumatology"
DOI: 10.1007/s10067-021-05900-7
Abstract: Systemic sclerosis (SSc) is a systemic multi-organ disease. Raynaud’s phenomenon (RP) and digital ulcers (DUs) in SSc patients can be resistant to usual treatments. We studied the clinical benefits, capillaroscopy changes, and cost-effectiveness of local…
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Keywords:
prostaglandin;
capillaroscopy;
digital ulcers;
group ... See more keywords
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Published in 2025 at "Clinical Rheumatology"
DOI: 10.1007/s10067-025-07449-1
Abstract: Digital ulcers (DU) are one of the most frequent manifestations in systemic sclerosis (SSc). The presence of DU seems to be a sentinel sign of internal organ involvement and is related to a poor prognosis…
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Keywords:
rheumatology;
presence;
ssc;
digital ulcers ... See more keywords
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Published in 2021 at "Chest"
DOI: 10.1016/j.chest.2020.09.076
Abstract: CASE PRESENTATION A 54-year-old man who had worked in a cement factory for the past 30 years, presented to the chest clinic with complaints of insidious onset, gradually progressive breathlessness with intermittent dry cough of…
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Keywords:
breathlessness;
digital ulcers;
factory worker;
history ... See more keywords
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Published in 2024 at "Rheumatology"
DOI: 10.1093/rheumatology/keae163.171
Abstract: Digital Ulcers (DU) affect around half of systemic sclerosis (SSc) patients and are associated with significant pain and difficulties in daily life. Despite available treatment options, DUs are often recalcitrant and recurrent. Our aim was…
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Keywords:
treatment;
none;
needs treatment;
unmet needs ... See more keywords
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Published in 2017 at "Rheumatology"
DOI: 10.1093/rheumatology/kex045
Abstract: Objective Colour Doppler ultrasonography (CDUS) is very important in general vascular diagnostic procedures. Its role in determining the extent of vasculopathy in Systemic Sclerosis (SSc) needs further investigation. The aim of this study was to…
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Keywords:
vasculopathy systemic;
digital ulcers;
cdus;
systemic sclerosis ... See more keywords
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Published in 2019 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.13554
Abstract: Low levels of vitamin D (25OHD) have been found to associated with digital ulcers (DUs) in systemic sclerosis (SSc), although only cross‐sectional studies have been performed. We aimed to investigate if variations in vitamin D…
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Keywords:
serum levels;
vitamin serum;
systemic sclerosis;
digital ulcers ... See more keywords
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Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.4902
Abstract: Background Digital ulcers (DUs) are common manifestations of vascular disease in systemic sclerosis (Ssc) patients. Objectives To investigate the association between the amount of oxygen delivered to periferal tissues and the development of DUs in…
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Keywords:
oxygen;
ssc patients;
digital ulcers;
tissue oxygen ... See more keywords
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Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.5177
Abstract: Background Skin ulcers are a frequent manifestation of systemic sclerosis (SSc). Skin ulcers are painful, represent a cause of disability and heavily affect patients’ quality of life. The presence of local infection may be responsible…
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Keywords:
ssc patients;
digital ulcers;
ssc;
systemic sclerosis ... See more keywords
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Published in 2024 at "Journal of Scleroderma and Related Disorders"
DOI: 10.1177/23971983241285206
Abstract: Introduction: Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by fibrosis and vascular abnormalities, often leading to the development of digital ulcers (DUs). DUs are painful and debilitating, significantly impacting patients’ quality of life.…
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Keywords:
mepivacaine;
pain management;
pain;
digital ulcers ... See more keywords
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Published in 2025 at "Journal of Scleroderma and Related Disorders"
DOI: 10.1177/23971983251343459
Abstract: Objective: The objective of this study is to examine the efficacy of ultrasonography in evaluating and tracking the healing process of digital ulcers in patients with systemic sclerosis. Methods: The study cohort comprised 23 patients…
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Keywords:
correlation;
healing process;
digital ulcers;
ultrasonography ... See more keywords
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Published in 2022 at "BMC Musculoskeletal Disorders"
DOI: 10.1186/s12891-022-05145-8
Abstract: Background Systemic sclerosis (SSc) is a rare connective tissue disease characterised by immune dysfunction, vasculopathy, cellular inflammation, fibrosis of the skin associated with multiple internal organs involvement. Ischaemic digital ulcers (IDU) of the hands commonly…
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Keywords:
systemic sclerosis;
study;
ischaemic digital;
digital ulcers ... See more keywords