Design, synthesis and MAO inhibitory activity of 2-(arylmethylidene)-2,3-dihydro-1-benzofuran-3-one derivatives
Sign Up to like & getrecommendations! Published in 2017 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2017.02.009
Abstract: Abstract A series of 2-(arylmethylidene)-2,3-dihydro-1-benzofuran-3-one derivatives (aurones, 1–20 ) were synthesized and screened for their inhibitory activity against hMAO. Seventeen compounds ( 1 – 5 , 7 – 17 , 19 ) were found to… read more here.
Keywords: benzofuran one; one derivatives; arylmethylidene dihydro; dihydro benzofuran ... See more keywords
Pharmacological Characterization of 5-Substituted 1-[(2,3-dihydro-1-benzofuran-2-yl)methyl]piperazines: Novel Antagonists for the Histamine H3 and H4 Receptors with Anti-inflammatory Potential
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2017.00825
Abstract: The histamine receptors (HRs) are traditional G protein-coupled receptors of extensive therapeutic interest. Recently, H3R and H4R subtypes have been targeted in drug discovery projects for inflammation, asthma, pain, cancer, Parkinson’s, and Alzheimer’s diseases, which… read more here.
Keywords: anti inflammatory; benzofuran methyl; dihydro benzofuran; histamine receptors ... See more keywords