Novel 1,4-Dihydro-2H-pyrano[3,4‑c]quinoline Compounds for Treating Bacterial Infections, Tuberculosis, or Leprosy.
Sign Up to like & getrecommendations! Published in 2025 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.5c00637
Abstract: Provided herein are novel 1,4-dihydro-2H-pyrano-[3,4-c]-quinoline compounds, pharmaceutical compositions, use of such compounds in treating bacterial infections, tuberculosis or leprosy, and processes for preparing such compounds. read more here.
Keywords: treating bacterial; pyrano quinoline; compounds treating; dihydro pyrano ... See more keywords
Synthetic utility of 4-chloro-2,5-dioxo-6-phenyl-5,6-dihydro-2H-pyrano[3,2-c]quinoline-3-carbaldehyde and molecular docking and cytotoxicity of its derivatives
Sign Up to like & getrecommendations! Published in 2025 at "Synthetic Communications"
DOI: 10.1080/00397911.2025.2588178
Abstract: Abstract A novel 4-chloro-2,5-dioxo-6-phenyl-5,6-dihydro-2H-pyrano[3,2-c]quinoline-3-carbaldehyde was synthesized via the Vilsmeier reaction and served as a key intermediate for constructing a series of heterocyclic quinoline derivatives. Modification of the pyranoquinoline-3-carbaldehyde scaffold through subsequent reactions with hydrazines, o-phenylenediamine,… read more here.
Keywords: pyrano quinoline; dihydro pyrano; chloro dioxo; carbaldehyde ... See more keywords
Silica-Supported Ionic Liquids Prompted One-Pot Four-Component Synthesis of Pyrazolopyranopyrimidines, 3-methyl-4-aryl-4,5-dihydro-1H-pyrano[2,3-c]pyrazol-6-ones, and 1,6-diamino-2-oxo-1,2,3,4-tetrahydropyridine-3,5-dicarbonitriles
Sign Up to like & getrecommendations! Published in 2017 at "Polycyclic Aromatic Compounds"
DOI: 10.1080/10406638.2015.1112821
Abstract: ABSTRACT Three methods have been used for synthesis of pyrazolopyranopyrimidines, 3-methyl-4-aryl-4,5-dihydro-1H-pyrano[2,3-c]pyrazol-6-ones, and 1,6-diamino-2-oxo-1,2,3,4-tetrahydropyridine-3,5-dicarbonitrile derivatives via four-component reactions under solvent-free conditions. Silica-bonded 5-n-propyl-octahydro-pyrimido[1,2-a]azepiniumchloride (SB-DBU+Cl−), silica-bonded n-propyl-4-aza-1-azoniabicyclo[2.2.2]octane chloride (SB-DABCO+Cl−), and nano silica-bonded 5-n-propyl-octahydro-pyrimido[1,2-a]azepinium chloride (NSB-DBU+Cl−) as silica-supported… read more here.
Keywords: aryl dihydro; pyrazolopyranopyrimidines methyl; pyrano pyrazol; dihydro pyrano ... See more keywords
Synthesis of Novel Biologically Important 5-Amino-2-Oxo-7-Aryl-3,7-Dihydro-2H-Pyrano[2,3-d]Thiazole-6-Carbonitriles in Trifluoroethanol (TFE) under Ultrasound Irradiation Condition and Their Antimicrobial Activity
Sign Up to like & getrecommendations! Published in 2020 at "Polycyclic Aromatic Compounds"
DOI: 10.1080/10406638.2019.1711432
Abstract: A series of novel 5-amino-2-oxo-7-aryl-3,7-dihydro-2H-pyrano[2,3-d]thiazole-6-carbonitriles 5a–j have been synthesized by adopting a facile and simple methodology. The reaction of monochloroacetic ... read more here.
Keywords: pyrano thiazole; amino oxo; aryl dihydro; oxo aryl ... See more keywords
Zn[L-proline]2 as an Efficient Catalyst for the Synthesis of Dihydro Pyrano Thiazole Derivatives via Cycloaddition Reaction in Aqueous Medium
Sign Up to like & getrecommendations! Published in 2024 at "Current Organic Chemistry"
DOI: 10.2174/0113852728295316240325041145
Abstract: In the current study, a zinc-linked amino acid complex was successfully synthesized as an efficient and recoverable catalyst for the synthesis of dihydro pyrano thiazole derivatives via the reaction of an aromatic aldehyde with malononitrile… read more here.
Keywords: reaction; catalyst; dihydro pyrano; pyrano thiazole ... See more keywords