Meglumine catalyzed one-pot green synthesis of novel 4,7-dihydro-1H-pyrazolo[3,4-b]pyridin-6-amines
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DOI: 10.1016/j.cclet.2016.09.013
Abstract: Abstract Meglumine efficiently catalyzes the one-pot, five-component reaction of hydrazine, ethyl acetoacetate, aryl aldehydes, substituted phenylacetonitriles and ammonium acetate in ethanol at room temperature to afford novel 4,7-dihydro-1 H -pyrazolo[3,4-b]pyridin-6-amine derivatives. The present approach offers… read more here.
Keywords: pyrazolo pyridin; dihydro pyrazolo; novel dihydro; one pot ... See more keywords
Unexpected formation of 4,5-dihydro-1H-pyrazolo[3,4-b]pyridine derivatives as a potent antitubercular agent and its evaluation by green chemistry metrics
Sign Up to like & getrecommendations! Published in 2018 at "Synthetic Communications"
DOI: 10.1080/00397911.2018.1524491
Abstract: Abstract The present study describes L-hydroxy proline catalyzed unpredicted formation of 4,5-dihydro-1H-pyrazolo[3,4-b]pyridines instead of expected 4,7-dihydro-1H-pyrazolo[3,4-b]pyridines in aqueous ethanol at ambient temperature through one-pot three-component reaction. Furthermore, this protocol was evaluated using green chemistry metrics… read more here.
Keywords: chemistry metrics; dihydro pyrazolo; chemistry; formation dihydro ... See more keywords