Synthesis and Antitumor Activities of Novel Mitochondria-Targeted Dihydroartemisinin Ether Derivatives
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DOI: 10.1021/acsomega.2c04562
Abstract: Ten novel mitochondria-targeted dihydroartemisinin ether derivatives were designed, synthesized, and evaluated for antitumor activity against five cancer cell lines in vitro. Profoundly, compound D8-T (IC50 = 56.9 nM) showed the most potent antiproliferative activity against… read more here.
Keywords: cell; targeted dihydroartemisinin; dihydroartemisinin ether; mitochondria targeted ... See more keywords