Concise asymmetric total syntheses of (−)-nuciferol, (−)-nuciferal, and (−)-dihydrocurcumene via Rh(I)-catalyzed boronic acid addition
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DOI: 10.1016/j.tetlet.2020.152790
Abstract: Abstract A general catalytic asymmetric total synthesis of aromatic bisabolane sesquiterpenes, (−)-nuciferol (ent-1c), (−)-nuciferal (ent-1d), and (−)-dihydrocurcumene (ent-1h) have been achieved in 5–6 steps in high chemical yields from commercially available (E)-ethylcrotonate. A key catalytic… read more here.
Keywords: asymmetric total; boronic acid; acid addition; dihydrocurcumene ... See more keywords