Ready access to 7,8-dihydroindolo[2,3-d][1]benzazepine-6(5H)-one scaffold and analogues via early-stage Fischer ring-closure reaction
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DOI: 10.3762/bjoc.18.15
Abstract: Paullone isomers are known as inhibitors of tubulin polymerase and cyclin dependent kinases (Cdks), which are potential targets for cancer chemotherapy. Herein we report an efficient and clean pathway to the fourth isomer, which remained… read more here.
Keywords: dihydroindolo benzazepine; access dihydroindolo; reaction; benzazepine one ... See more keywords