Asymmetric Synthesis of Dihydropyranones with Three Contiguous Stereocenters by an NHC‐Catalyzed Kinetic Resolution
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DOI: 10.1002/ejoc.202100491
Abstract: An oxidative NHC-catalyzed kinetic resolution (KR) of racemic mixtures is presented. The developed reaction furnishes tricyclic dihydropyranones with three contiguous stereocenters in excellent dia- and enantioselectivity, with good-to-moderate yields. Mechanistic studies indicate that the rate-determining… read more here.
Keywords: three contiguous; kinetic resolution; dihydropyranones three; catalyzed kinetic ... See more keywords