Anticancer activity of a 1,4-dihydropyridine in DMBA-induced mouse skin tumor model
Sign Up to like & getrecommendations! Published in 2020 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000000887
Abstract: Antitumor potential of a 1,4-dihydropyridine derivative (DHP-8) has been successfully studied previously in a number of cancer cell lines including the human melanoma cells, A375. In order to validate its anticancer activity, DMBA induced tumor… read more here.
Keywords: dmba; dihydropyridine; cancer; dmba induced ... See more keywords
Effect of dihydropyridine calcium channel blockers on blood pressure variability in the SPRINT trial: a treatment effects approach
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Hypertension"
DOI: 10.1097/hjh.0000000000003033
Abstract: Supplemental Digital Content is available in the text Objective: Increased visit-to-visit blood pressure variability (vvBPV) has negative effects on multiple organ systems. Prior research has suggested that dihydropyridine calcium channel blockers (CCB) may reduce vvBPV,… read more here.
Keywords: blood pressure; sprint trial; dihydropyridine; dihydropyridine ccb ... See more keywords
Synthesis of diethyl 4-(phenyl-substituted)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates catalyzed by CoCl2/K-10 montmorillonite in water and their antimicrobial activity
Sign Up to like & getrecommendations! Published in 2017 at "Russian Journal of General Chemistry"
DOI: 10.1134/s1070363217030264
Abstract: A simple and efficient method of one pot synthesis of 1,4-dihydropyridine by three components reaction of aromatic aldehydes with 1,3-dicarbonyl compound, ammonium acetate and catalytic amount of CoCl2 based on the Hantszch reaction is developed.… read more here.
Keywords: dihydropyridine; water; antimicrobial activity; synthesis ... See more keywords
Effects of Long- and Intermediate-Acting Dihydropyridine Calcium Channel Blockers in Hypertension
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DOI: 10.1177/1074248418771341
Abstract: Background: Dihydropyridine calcium channel blockers are a heterogeneous group of antihypertensive drugs. Long-acting dihydropyridine agent amlodipine is widely used for monotherapy and combination therapy for hypertension in clinical practice, while intermediate-acting dihydropyridine agents have shown… read more here.
Keywords: dihydropyridine calcium; dihydropyridine; risk; calcium channel ... See more keywords
Design and synthesis of novel dihydropyridine- and benzylideneimine-based tyrosinase inhibitors
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2024.1332184
Abstract: Tyrosinase (TYR) inhibitors are very significant as they inhibit enzyme tyrosinase activity, and its inhibition is vital for skin care, anticancer medication, and antibrowning of fruits and vegetables. This work presents a novel and economical… read more here.
Keywords: dihydropyridine; tyrosinase; tyrosinase inhibitors; design synthesis ... See more keywords