Axially chiral 1,4-dihydropyridine derivatives: aggregation-induced emission in exciplexes and application as viscosity probes
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DOI: 10.1039/c9ra06553a
Abstract: Axially chiral 1,4-dihydropyridine derivatives ((R)-/(S)-2) with aggregation-induced emission (AIE) in exciplex were designed and synthesized. They have excellent CD signals and can determine the different viscosity in mixed solvents. read more here.
Keywords: aggregation induced; derivatives aggregation; dihydropyridine derivatives; chiral dihydropyridine ... See more keywords
Organocatalyzed highly efficient synthesis of densely functionalized pyrrole-fused 1,4-dihydropyridine derivatives
Sign Up to like & getrecommendations! Published in 2019 at "Synthetic Communications"
DOI: 10.1080/00397911.2019.1647440
Abstract: Abstract An organo base catalyzed diverse pyrrole-fused 1,4-dihydropyridines were synthesized. This one-pot, three-component domino reaction of enamino imides, aromatic aldehydes, and malononitrile/ethyl cyanoacetate was achieved by 10 mol% of DMAP under refluxing ethanol. In addition, novel… read more here.
Keywords: organocatalyzed highly; pyrrole; dihydropyridine derivatives; fused dihydropyridine ... See more keywords
Current Status on 1,4-Dihydropyridine Derivatives against Human Pathogenic Parasites.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867330666221104162901
Abstract: Infections provoked by parasites are among the most prevalent diseases worldwide and generate important health and socioeconomic problems. Despite the enormous amount of work done, the chemotherapy for most of them remains unsolved. Usually, treatments… read more here.
Keywords: dihydropyridine derivatives; derivatives human; pathogenic parasites; human pathogenic ... See more keywords
Synthesis of efficient cobalt–metal organic framework as reusable nanocatalyst in the synthesis of new 1,4-dihydropyridine derivatives with antioxidant activity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.932902
Abstract: Efficient cobalt–metal organic framework (Co-MOF) was prepared via a controllable microwave-assisted reverse micelle synthesis route. The products were characterized by SEM image, N2 adsorption/desorption isotherm, FTIR spectrum, and TG analysis. Results showed that the products… read more here.
Keywords: dihydropyridine derivatives; antioxidant activity; cobalt metal; efficient cobalt ... See more keywords
Novel 1,4-Dihydropyridine Derivatives as Mineralocorticoid Receptor Antagonists
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032439
Abstract: The mineralocorticoid receptor (MR) belongs to the steroid receptor subfamily of nuclear receptors. MR is a transcription factor key in regulating blood pressure and mineral homeostasis. In addition, it plays an important role in a… read more here.
Keywords: novel dihydropyridine; dihydropyridine derivatives; receptor antagonists; derivatives mineralocorticoid ... See more keywords
One-pot multicomponent green Hantzsch synthesis of 1,2-dihydropyridine derivatives with antiproliferative activity
Sign Up to like & getrecommendations! Published in 2020 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.16.235
Abstract: A rapid route for obtaining unsymmetrical 1,2-dihydropyridines (1,2-DHPs) as opposed to 1,4-dihydropyridines (1,4-DHPs) has been achieved via a one-pot multicomponent Hantzsch reaction. A benign protocol has been developed for the preparation of various 1,2-dihydropyridine derivatives… read more here.
Keywords: pot multicomponent; dihydropyridine derivatives; antiproliferative activity; one pot ... See more keywords
In vitro bactericidal activities of two novel dihydropyridine derivatives against Mycobacterium tuberculosis.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of infection in developing countries"
DOI: 10.3855/jidc.7966
Abstract: INTRODUCTION Introducing new and effective antitubercular agents is important in tuberculosis control programs. In this study, the in vitro antitubercular activity of two novel 1,4-dihydropyridine derivatives (F-27, Cl-33) were screened against a total of 113… read more here.
Keywords: novel dihydropyridine; dihydropyridine derivatives; tuberculosis; two novel ... See more keywords