Dihydropyrimidone Derivatives as Thymidine Phosphorylase Inhibitors: Inhibition Kinetics, Cytotoxicity, and Molecular Docking
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DOI: 10.3390/molecules28083634
Abstract: Overexpression of the thymidine phosphorylase (TP) enzyme induces angiogenesis, which eventually leads to metastasis and tumor growth. The crucial role of TP in cancer development makes it an important target for anticancer drug discovery. Currently,… read more here.
Keywords: molecular docking; cytotoxicity; dihydropyrimidone; dihydropyrimidone derivatives ... See more keywords