ONE-POT DIASTEREOSELECTIVE SYNTHESIS OF FUNCTIONALIZED 4,5-DIHYDROPYRROLES BY REACTIONS OF ARYLGLYOXALS, β-DICARBONYL COMPOUNDS, AND AROMATIC AMINES
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DOI: 10.1007/5055
Abstract: A multicomponent reaction of arylglyoxal hydrates, acetylacetone or acetoacetic ester, aniline or its 3(4)-substituted analogs in 1:1:2 ratio occurred upon stirring in methanol, giving 4-arylamino-5-hydroxypyrroline derivatives containing 4,5-dihydroxypyrrolines as impurities. read more here.
Keywords: diastereoselective synthesis; synthesis functionalized; functionalized dihydropyrroles; dihydropyrroles reactions ... See more keywords