A heterogeneous catalytic and solvent-free approach to 1,2-dihydroquinoline derivatives from aromatic amines and alkynes by tandem hydroarylation-hydroamination
Sign Up to like & getrecommendations! Published in 2020 at "Catalysis Communications"
DOI: 10.1016/j.catcom.2019.105888
Abstract: Abstract This study describes a mesoporous aluminosilicate (ASM) catalyst-induced one-step synthesis of substituted dihydroquinolines through a hydroarylation/hydroamination cascade reaction under solvent-free conditions. A sol-gel method was utilized to prepare the ASM catalyst using tetraethyl orthosilicate… read more here.
Keywords: dihydroquinoline derivatives; solvent free; hydroarylation hydroamination;
7-Hydroxy-4-phenyl-1, 2-dihydroquinoline derivatives: synthesis via one-pot, three-component reaction and structure elucidation
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DOI: 10.1016/j.heliyon.2020.e05035
Abstract: We have developed a new and facile one pot three component protocol catalyzed by ammonium acetate for construction of new functionalized 7-hydroxy-4-phenyl-1,2-dihydroquinoline derivatives. A variety of quinoline derivatives were obtained in good to excellent yield… read more here.
Keywords: hydroxy phenyl; dihydroquinoline derivatives; three component; one pot ... See more keywords
Machine learning prediction of the potential pesticide applicability of three dihydroquinoline derivatives: Syntheses, crystal structures and physical properties
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DOI: 10.1016/j.molstruc.2020.127732
Abstract: Abstract Increasingly machine learning processes have been applied in the search and development of compounds that may have specific physicochemical properties to the desired application. This article describes how a machine learning model led us… read more here.
Keywords: machine learning; dihydroquinoline derivatives; pesticide; three dihydroquinoline ... See more keywords
Transferrin-conjugated liposomes loaded with novel dihydroquinoline derivatives as potential anticancer agents
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DOI: 10.1371/journal.pone.0186821
Abstract: A series of 1,2-dihydroquinoline derivatives were synthesized and evaluated for cytotoxicity in HeLa, Hep G2 and 6HEK-293T cell lines. EEDQ2 was identified as a promising anti-cancer agent with low IC50 in HeLa (18.55μg/ml) and Hep… read more here.
Keywords: dihydroquinoline derivatives; transferrin conjugated; liposomes loaded; conjugated liposomes ... See more keywords