1,3-Dipolar cycloaddition reaction for diastereoselective synthesis of functionalized dihydrospiro[indoline-3,2′-pyrroles]
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DOI: 10.1016/j.cclet.2016.07.016
Abstract: Abstract The BF3OEt2 catalyzed one-pot 1,3-dipolar cycloaddition reaction of benzylamines, isatins and dimethyl acetylenedicarboxylate in dry methylene dichloride afforded the functionalized dihydrospiro[indoline-3,2′-pyrroles] in moderate to good yields and with high diastereoselectivity. The reaction was accomplished… read more here.
Keywords: cycloaddition; cycloaddition reaction; dihydrospiro indoline; reaction ... See more keywords