Synthesis and analysis of dihydrotetrabenazine derivatives as novel vesicular monoamine transporter 2 inhibitors.
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DOI: 10.1016/j.ejmech.2021.113718
Abstract: Vesicular monoamine transporter 2 (VMAT2) is essential for synaptic transmission of all biogenic amines in the brain including serotonin, norepinephrine, histamine, and dopamine (DA). Given its crucial role in the neurophysiology and pharmacology of the… read more here.
Keywords: monoamine transporter; vesicular monoamine; synthesis analysis; dihydrotetrabenazine ... See more keywords