Association of a reactive intermediate derived from 1′,6‐dihydroxy metabolite with benzbromarone‐induced hepatotoxicity
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DOI: 10.1002/jbt.21946
Abstract: Treatment with benzbromarone can be associated with liver injury, but the detailed mechanism remains unknown. Our recent studies demonstrated that benzbromarone was metabolized to 1′,6‐dihydroxybenzbromarone and followed by formation of reactive intermediates that were trapped… read more here.
Keywords: reactive intermediate; intermediate derived; liver injury; benzbromarone ... See more keywords