10β,17α-Dihydroxyestra-1,4-dien-3-one: A Bioprecursor Prodrug Preferentially Producing 17α-Estradiol in the Brain for Targeted Neurotherapy.
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DOI: 10.1021/acschemneuro.8b00184
Abstract: Uterotrophic effect of 17α-estradiol, the C17 epimer of the main human estrogen 17β-estradiol, was shown to manifest in animal models at doses lower than those necessary for central outcome raising concerns about its potential to… read more here.
Keywords: estradiol; producing estradiol; dihydroxyestra dien; bioprecursor prodrug ... See more keywords