One-pot synthesis of 2,3-disubstituted benzofurans from 2-chlorophenols using palladium–dihydroxyterphenylphosphine catalyst
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DOI: 10.1016/j.tetlet.2018.07.019
Abstract: Abstract 2,3-Disubstituted benzofurans possessing 2-hydroxyphenyl moiety at the C-3 position were synthesized from readily available 2-chlorophenols and terminal alkynes by hydroxy-directed ortho-Sonogashira coupling and subsequent oxypalladation/reductive elimination, using Pd-dihydroxyterphenylphosphine catalyst. The catalyst accelerates not only… read more here.
Keywords: pot synthesis; dihydroxyterphenylphosphine catalyst; synthesis disubstituted; one pot ... See more keywords