I2/TBHP-Promoted Approach to α-Keto Esters from Trifluoromethyl β-Diketones and Alcohols via C–C Bond Cleavage
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DOI: 10.1055/s-0036-1588833
Abstract: A metal-free oxidative coupling reaction of trifluoromethyl β-diketones with alcohols for the synthesis of α-keto esters in good to excellent yields has been developed. Preliminary mechanistic studies suggest that an I2/TBHP promoted sequential iodination, C–C… read more here.
Keywords: diketones alcohols; bond; tbhp promoted; keto esters ... See more keywords