Desymmetrization of Cyclic 1,3-Diketones under N-Heterocyclic Carbene Organocatalysis: Access to Organofluorines with Multiple Stereogenic Centers
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DOI: 10.34133/2021/9867915
Abstract: Symmetric 1,3-diketones with fluorine or fluorinated substituents on the prochiral carbon remain to be established. Herein, we have developed a novel prochiral fluorinated oxindanyl 1,3-diketone and successfully applied these substrates in carbene-catalyzed asymmetric desymmetrization. Accordingly,… read more here.
Keywords: desymmetrization cyclic; cyclic diketones; diketones heterocyclic; multiple stereogenic ... See more keywords