Association of Titin Variations With Late-Onset Dilated Cardiomyopathy.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2021.5890
Abstract: Importance Dilated cardiomyopathy (DCM) is frequently caused by genetic factors. Studies identifying deleterious rare variants have predominantly focused on early-onset cases, and little is known about the genetic underpinnings of the growing numbers of patients… read more here.
Keywords: late onset; titin; onset dcm; dilated cardiomyopathy ... See more keywords
The aptamer BC 007 for treatment of dilated cardiomyopathy: evaluation in Doberman Pinschers of efficacy and outcomes
Sign Up to like & getrecommendations! Published in 2020 at "ESC Heart Failure"
DOI: 10.1002/ehf2.12628
Abstract: Aptamer BC 007, a 15‐mer single‐strand DNA oligonucleotide (5'‐GGTTGGTGTGGTTGG‐3'), was developed to neutralize functional autoantibodies that bind to the extracellular domains of G protein‐coupled receptors (GPCR‐AAB), leading to the modulation of receptor‐mediated signalling cascades that… read more here.
Keywords: aptamer 007; treatment dilated; dilated cardiomyopathy; cardiomyopathy evaluation ... See more keywords
Myocardial ultrastructure can augment genetic testing for sporadic dilated cardiomyopathy with initial heart failure.
Sign Up to like & getrecommendations! Published in 2021 at "ESC heart failure"
DOI: 10.1002/ehf2.13596
Abstract: AIMS The aim of the present study was to consider whether the ultrastructural features of cardiomyocytes in dilated cardiomyopathy can be used to guide genetic testing. METHODS AND RESULTS Endomyocardial biopsy and whole-exome sequencing were… read more here.
Keywords: dilated cardiomyopathy; genetic testing; sporadic dilated; heart failure ... See more keywords
Nomogram predicting death and heart transplantation before appropriate ICD shock in dilated cardiomyopathy
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13808
Abstract: This study aimed to develop and validate a competing risk nomogram for predicting all‐cause mortality and heart transplantation (HT) before first appropriate shock in non‐ischaemic dilated cardiomyopathy (DCM) patients receiving implantable cardioverter‐defibrillators (ICD). read more here.
Keywords: nomogram predicting; shock; heart; heart transplantation ... See more keywords
Serum autotaxin as a novel prognostic marker in patients with non‐ischaemic dilated cardiomyopathy
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13817
Abstract: Autotaxin (ATX) promotes myocardial inflammation, fibrosis, and the subsequent cardiac remodelling through lysophosphatidic acid production. However, the prognostic impact of serum ATX in non‐ischaemic dilated cardiomyopathy (NIDCM) has not been clarified. We investigated the prognostic… read more here.
Keywords: ischaemic dilated; dilated cardiomyopathy; serum autotaxin; non ischaemic ... See more keywords
Changes in clinical and imaging variables during withdrawal of heart failure therapy in recovered dilated cardiomyopathy
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DOI: 10.1002/ehf2.13872
Abstract: This study aimed to profile the changes in non‐invasive clinical, biochemical, and imaging markers during withdrawal of therapy in patients with recovered dilated cardiomyopathy, providing insights into the pathophysiology of relapse. read more here.
Keywords: heart failure; imaging; therapy; recovered dilated ... See more keywords
Myocardial recovery evaluation from ventricular assist device in patients with dilated cardiomyopathy
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DOI: 10.1002/ehf2.13951
Abstract: The removal of left ventricular assist device (LVAD) after myocardial recovery can provide survival benefits with freedom from LVAD‐associated complications. However, in the absence of standardization, the weaning evaluation and surgical strategy differ widely among… read more here.
Keywords: evaluation; myocardial recovery; ventricular assist; assist device ... See more keywords
Angiotensin receptor‐neprilysin inhibitor in symptomatic patients with Duchenne dilated cardiomyopathy: A primetime
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13963
Abstract: Duchenne muscular dystrophy (DMD) is an X‐linked recessive neuromuscular disorder, characterized by significant long‐term cardiac involvement. Dilated cardiomyopathy (DCM) is the main cause of death in DMD, and angiotensin‐converting enzyme inhibitors (ACEi) and beta‐blockers (BB)… read more here.
Keywords: angiotensin; neprilysin inhibitor; receptor neprilysin; angiotensin receptor ... See more keywords
Clinical characterization and natural history of chemotherapy‐induced dilated cardiomyopathy
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DOI: 10.1002/ehf2.14045
Abstract: Chemotherapy‐induced dilated cardiomyopathy (CI‐DCM) is a well‐recognized phenotype of non‐ischemic dilated cardiomyopathy (DCM), characterized by poor outcomes. However, a detailed comparison between idiopathic DCM (iDCM) and CI‐DCM is still lacking. read more here.
Keywords: chemotherapy induced; clinical characterization; induced dilated; dilated cardiomyopathy ... See more keywords
Gender medicine in dilated cardiomyopathy: pride and prejudice
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.1280
Abstract: Non-ischaemic dilated cardiomyopathy (DCM), despite its apparently simple definition, incorporates several aetiologies. Currently, the advent of next-generation sequencing techniques has demonstrated that genetic mutations are responsible for approximately 50% of DCM. In the remaining cases,… read more here.
Keywords: medicine; dcm; gender; medicine dilated ... See more keywords
Prognostic impact of short‐term changes of E/E' ratio and left atrial size in dilated cardiomyopathy
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.1543
Abstract: Left ventricular reverse remodelling (LVRR) has been validated as a key prognostic tool in dilated cardiomyopathy (DCM).1,2 However, it has been described that LVRR may take up to 2 years following diagnosis.1 Therefore, new parameters… read more here.
Keywords: impact short; dcm patients; dilated cardiomyopathy; prognostic impact ... See more keywords