Enhanced Oral Bioavailability of Diltiazem by the Influence of Gallic Acid and Ellagic Acid in Male Wistar Rats: Involvement of CYP3A and P‐gp Inhibition
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DOI: 10.1002/ptr.5873
Abstract: The oral bioavailability of diltiazem is very low due to rapid first pass metabolism in liver and intestine. The purpose of the study was to investigate the effect of gallic acid and ellagic acid on… read more here.
Keywords: ellagic acid; oral bioavailability; bioavailability diltiazem; diltiazem ... See more keywords
Comparative Efficacy and Safety of Intravenous Verapamil and Diltiazem for Rate Control in Rapidly Conducted Atrial Fibrillation and Atrial Flutter
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DOI: 10.1007/s11606-020-06051-2
Abstract: Beta-blockers and non-dihydropyridine calcium channel blockers (CCBs) are first-line therapy for heart rate (HR) control in atrial fibrillation (AF) and atrial flutter (AFL) . While diltiazem is used more frequently during inpatient practice than verapamil,… read more here.
Keywords: atrial fibrillation; diltiazem; rate control; fibrillation atrial ... See more keywords
ROLE OF DILTIAZEM IN SHORT-TERM OUTCOME OF LIVE RELATED RENAL TRANSPLANT HYPERTENSIVE RECIPIENTS WITH NON-SURGICAL DELAYED GRAFT FUNCTION
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DOI: 10.1097/01.tp.0000700272.47403.27
Abstract: Introduction: Diltiazem commonly use as antihypertensive agent, also reduces tacrolimus dose by decrease metabolism to achieve its therapeutic blood concentration in kidney transplant recipients (KTRs). This method has been practiced in several centers, including India,… read more here.
Keywords: delayed graft; graft function; diltiazem; live related ... See more keywords
Botulinum Toxin Injection Plus Topical Diltiazem for Chronic Anal Fissure: A Randomized Double-Blind Clinical Trial and Long-term Outcome.
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DOI: 10.1097/dcr.0000000000001983
Abstract: BACKGROUND Chemical sphincterotomy avoids the risk of permanent incontinence in the treatment of chronic anal fissure, but it does not reach the efficacy of surgery and recurrence is high. Drug combination has been proposed to… read more here.
Keywords: fissure; long term; botulinum toxin; diltiazem ... See more keywords
First Reported Case of Rhabdomyolysis Associated with Concomitant Use of Cyclosporin, Diltiazem, and Simvastatin
Sign Up to like & getrecommendations! Published in 2021 at "Indian Journal of Nephrology"
DOI: 10.4103/ijn.ijn_5_20
Abstract: Rhabdomyolysis is a syndrome with a wide range of symptoms ranging from asymptomatic raised serum creatinine kinase to life-threatening metabolic disturbances and acute kidney injury. A careful history taking and high clinical suspicion on drug-drug… read more here.
Keywords: diltiazem; simvastatin; case rhabdomyolysis; rhabdomyolysis ... See more keywords