Asymmetric construction of densely functionalized three-dimensional aza-tetracyclic scaffolds for drug discovery.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc05700j
Abstract: Asymmetric construction of densely functionalized three-dimensional aza-tetracyclic scaffolds were achieved by intramolecular Diels-Alder reaction of bicyclic precursors derived from L-tyrosine. Three substituents were systematically introduced into the developed scaffolds in various combinations, demonstrating their high… read more here.
Keywords: construction densely; functionalized three; asymmetric construction; dimensional aza ... See more keywords