Articles with "dimensional culture" as a keyword



Three-dimensional co-culture microfluidic model and its application for research on cancer stem-like cells inducing migration of endothelial cells

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Published in 2017 at "Biotechnology Letters"

DOI: 10.1007/s10529-017-2363-9

Abstract: ObjectivesTo build a three-dimensional co-culture model in a microfluidic device for cancer research and evaluate its feasibility by investigating cancer stem-like cells (SCs) induced migration of human umbilical vein endothelial cells (ECs).ResultsThe microfluidic device provided… read more here.

Keywords: three dimensional; migration; model; dimensional culture ... See more keywords

Effect of NMDA receptor agonist and antagonist on spermatogonial stem cells proliferation in 2- and 3- dimensional culture systems.

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Published in 2022 at "Molecular biology reports"

DOI: 10.1007/s11033-021-07041-1

Abstract: BACKGROUND The main purpose of this study was to investigate the effect of D-serine (DS) and Dizocilpine (MK-801) on the proliferation of spermatogonial stem cells (SSCs) in two-dimensional (2D) and three-dimensional (3D) culture systems. METHODS… read more here.

Keywords: culture; spermatogonial stem; dimensional culture; stem cells ... See more keywords
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Three-dimensional culture models to study glioblastoma - current trends and future perspectives.

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Published in 2021 at "Current opinion in pharmacology"

DOI: 10.1016/j.coph.2021.08.019

Abstract: Glioblastoma (GBM) is the most prevalent form of primary malignant brain tumor in adults and remains almost invariably lethal owing to its aggressive and invasive nature. There have only been marginal improvements in its bleak… read more here.

Keywords: three dimensional; dimensional culture; biology; culture models ... See more keywords

Bioactive factors secreted from mesenchymal stromal cells protect the intestines from experimental colitis in a three-dimensional culture.

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Published in 2018 at "Cytotherapy"

DOI: 10.1016/j.jcyt.2018.06.007

Abstract: BACKGROUND AIMS Although mesenchymal stromal cells (MSCs) have shown therapeutic potential in intestinal tissue repair, controversy concerning their short survival and poor biodistribution in recipient tissues still remains. Therefore, we investigated the paracrine role of… read more here.

Keywords: three dimensional; mesenchymal stromal; stromal cells; colitis ... See more keywords

Three-dimensional (3D) culture of adult murine colon as an in vitro model of cryptosporidiosis: Proof of concept

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-17304-2

Abstract: Cryptosporidium parvum is a major cause of diarrheal illness and was recently potentially associated with digestive carcinogenesis. Despite its impact on human health, Cryptosporidium pathogenesis remains poorly known, mainly due to the lack of a… read more here.

Keywords: three dimensional; murine colon; model; dimensional culture ... See more keywords

Low concentrations of TNF-α in vitro transform the phenotype of vascular smooth muscle cells and enhance their survival in a three-dimensional culture system.

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Published in 2024 at "Artificial organs"

DOI: 10.1111/aor.14762

Abstract: BACKGROUND Vascular smooth muscle cells (VSMCs) are commonly used as seed cells in tissue-engineered vascular constructions. However, their variable phenotypes and difficult to control functions pose challenges. This study aimed to overcome these obstacles using… read more here.

Keywords: vascular smooth; culture; smooth muscle; three dimensional ... See more keywords
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Development of in vitro three‐dimensional co‐culture system for metabolic syndrome therapeutic agents

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Published in 2019 at "Diabetes"

DOI: 10.1111/dom.13628

Abstract: There are many obstacles to overcome in the development of new drugs for metabolic diseases, including efficacy and toxicity problems in later stages of drug development. To overcome these problems and predict efficacy and toxicity… read more here.

Keywords: three dimensional; development vitro; dimensional culture; development ... See more keywords

Three-Dimensional Culture Modelling Reveals Divergent Mycobacterium tuberculosis Virulence and Antimicrobial Treatment Response

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Published in 2024 at "Cellular Microbiology"

DOI: 10.1155/2024/6458900

Abstract: Tuberculosis (TB) remains a persistent epidemic, and the emergence of drug-resistant Mycobacterium tuberculosis (Mtb) presents a global healthcare threat. While some new agents have been successfully introduced, innovative technologies to evaluate emerging anti-TB compounds are… read more here.

Keywords: culture; tuberculosis; three dimensional; dimensional culture ... See more keywords

Ethanol Alters Phenotype and Synthesis Activity of Rat Neonatal Articular Chondrocytes Grown in 2- and 3-Dimensional Culture.

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Published in 2019 at "Cartilage"

DOI: 10.1177/1947603519870862

Abstract: OBJECTIVE We sought to evaluate the effect of different concentrations of ethanol on phenotype and activity of articular chondrocyte synthesis of neonatal rats in 2-dimensional (2D) and 3-dimensional (3D) culture. METHODS Chondrocytes were cultured in… read more here.

Keywords: dimensional culture; articular chondrocytes; treated ethanol; culture ... See more keywords

Three-dimensional Culture of Buffalo (Bubalus bubalis) Mammary Epithelial Cell Line

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Published in 2024 at "Indian Journal of Animal Research"

DOI: 10.18805/ijar.b-5442

Abstract: Background: The mammary gland is a crucial organ in dairy animals, responsible for milk production, regulated by intricate hormonal and cellular interactions. Traditional two-dimensional (2D) cell culture systems used in mammary gland research fail to… read more here.

Keywords: differentiation; mammary epithelial; culture; cell ... See more keywords

Effects of IGF-1 on the Three-Dimensional Culture of Ovarian Preantral Follicles and Superovulation Rates in Mice

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Published in 2022 at "Biology"

DOI: 10.3390/biology11060833

Abstract: Simple Summary In this experiment, mouse secondary follicles were cultured in the three-dimensional culture system of alginate gel with different concentrations of IGF-1. According to the results of follicle growth, oocyte maturation, the levels of… read more here.

Keywords: culture; number ovulated; superovulation; three dimensional ... See more keywords