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Published in 2017 at "Biotechnology Letters"
DOI: 10.1007/s10529-017-2363-9
Abstract: ObjectivesTo build a three-dimensional co-culture model in a microfluidic device for cancer research and evaluate its feasibility by investigating cancer stem-like cells (SCs) induced migration of human umbilical vein endothelial cells (ECs).ResultsThe microfluidic device provided… read more here.
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Published in 2022 at "Molecular biology reports"
DOI: 10.1007/s11033-021-07041-1
Abstract: BACKGROUND The main purpose of this study was to investigate the effect of D-serine (DS) and Dizocilpine (MK-801) on the proliferation of spermatogonial stem cells (SSCs) in two-dimensional (2D) and three-dimensional (3D) culture systems. METHODS… read more here.
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Published in 2021 at "Current opinion in pharmacology"
DOI: 10.1016/j.coph.2021.08.019
Abstract: Glioblastoma (GBM) is the most prevalent form of primary malignant brain tumor in adults and remains almost invariably lethal owing to its aggressive and invasive nature. There have only been marginal improvements in its bleak… read more here.
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Published in 2018 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2018.06.007
Abstract: BACKGROUND AIMS Although mesenchymal stromal cells (MSCs) have shown therapeutic potential in intestinal tissue repair, controversy concerning their short survival and poor biodistribution in recipient tissues still remains. Therefore, we investigated the paracrine role of… read more here.
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Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-17304-2
Abstract: Cryptosporidium parvum is a major cause of diarrheal illness and was recently potentially associated with digestive carcinogenesis. Despite its impact on human health, Cryptosporidium pathogenesis remains poorly known, mainly due to the lack of a… read more here.
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Published in 2019 at "Diabetes"
DOI: 10.1111/dom.13628
Abstract: There are many obstacles to overcome in the development of new drugs for metabolic diseases, including efficacy and toxicity problems in later stages of drug development. To overcome these problems and predict efficacy and toxicity… read more here.
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Published in 2019 at "Cartilage"
DOI: 10.1177/1947603519870862
Abstract: OBJECTIVE We sought to evaluate the effect of different concentrations of ethanol on phenotype and activity of articular chondrocyte synthesis of neonatal rats in 2-dimensional (2D) and 3-dimensional (3D) culture. METHODS Chondrocytes were cultured in… read more here.
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Published in 2022 at "Biology"
DOI: 10.3390/biology11060833
Abstract: Simple Summary In this experiment, mouse secondary follicles were cultured in the three-dimensional culture system of alginate gel with different concentrations of IGF-1. According to the results of follicle growth, oocyte maturation, the levels of… read more here.
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Published in 2020 at "Cancers"
DOI: 10.3390/cancers12102800
Abstract: Simple Summary It is getting more and more clear that cancer cell culture models are switching from two-dimension to three-dimensional, in order to better reflect in vivo situations where tumor cells have to cope with… read more here.