Three-dimensional genome organization in epigenetic regulations: cause or consequence?
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in plant biology"
DOI: 10.1016/j.pbi.2021.102031
Abstract: The evolution of the nucleus is an evolutionary milestone. By enabling genome compartmentalization, it contributes to the fine-tuning of genome functions. The genome is partitioned into functional domains differing in spatial positioning and topological folding… read more here.
Keywords: three dimensional; dimensional genome; cause consequence; genome ... See more keywords
A stem cell marker KLF5 regulates CCAT1 via three-dimensional genome structure in colorectal cancer cells.
Sign Up to like & getrecommendations! Published in 2021 at "British journal of cancer"
DOI: 10.1038/s41416-021-01579-4
Abstract: BACKGROUND KLF5 plays a crucial role in stem cells of colorectum in cooperation with Lgr5 gene. In this study, we aimed to explicate a regulatory mechanism of the KLF5 gene product from a view of… read more here.
Keywords: three dimensional; dimensional genome; genome structure; klf5 ... See more keywords
Three-dimensional genome structure of a single cell
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aaz7774
Abstract: Chromosome organization in diploid cells reveals a structural basis for smell Since the 1880s, scientists such as Carl Rabl have been looking at cell nuclei under a microscope and speculating about their three-dimensional (3D) structure.… read more here.
Keywords: three dimensional; dimensional genome; genome structure; structure ... See more keywords