In Situ Identification of Secondary Structures in Unpurified Bombyx mori Silk Fibrils Using Polarized Two-Dimensional Infrared Spectroscopy
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01156
Abstract: The mechanical properties of biomaterials are dictated by the interactions and conformations of their building blocks, typically proteins. Although the macroscopic behaviour of biomaterials is widely studied, our understanding of the underlying molecular properties is… read more here.
Keywords: two dimensional; spectroscopy; silk; polarized two ... See more keywords
Unraveling dynamic protein structures by two-dimensional infrared spectra with a pretrained machine learning model
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2409257121
Abstract: Significance Unraveling dynamic protein structures from two-dimensional infrared (2DIR) spectral signals presents a formidable task. By utilizing machine learning, we have correlated the intricate 2DIR spectroscopic features with the protein dynamic conformations, thereby tracing changes… read more here.
Keywords: protein structures; unraveling dynamic; dimensional infrared; two dimensional ... See more keywords
AI protocol for retrieving protein dynamic structures from two-dimensional infrared spectra
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2424078122
Abstract: Significance Dynamic protein structures are essential for understanding their diverse biological functions. Two-dimensional infrared (2DIR) spectroscopy is a powerful technique for monitoring protein dynamics, yet converting spectroscopic signals into detailed 3D structures remains a challenge.… read more here.
Keywords: spectroscopy; retrieving protein; protocol retrieving; dimensional infrared ... See more keywords