Genome dimensions control biological and toxicological functions; myth or reality?
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DOI: 10.1007/s10565-018-9440-2
Abstract: The multidimensional genome offers a new perspective to understand molecular mechanisms of genotoxicity and provide deeper knowledge of how genome organization and reorganization in dimensions can alter cell sensitivity, tolerance, resistance, or toxicity to drugs,… read more here.
Keywords: control biological; genome dimensions; genome; dimensions control ... See more keywords
Dimensions of control for subthreshold oscillations and spontaneous firing in dopamine neurons
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1007375
Abstract: Dopaminergic neurons (DAs) of the rodent substantia nigra pars compacta (SNc) display varied electrophysiological properties in vitro. Despite this, projection patterns and functional inputs from DAs to other structures are conserved, so in vivo delivery… read more here.
Keywords: spontaneous firing; firing dopamine; control subthreshold; subthreshold oscillations ... See more keywords