Dimerization facilitates the conformational transitions for bacterial phosphotransferase enzyme I autophosphorylation in an allosteric manner
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12260
Abstract: The bacterial phosphotransferase system is central to sugar uptake and phosphorylation. Enzyme I (EI), the first enzyme of the system, autophosphorylates as a dimer using phosphoenolpyruvate (PEP), but it is not clearly understood how dimerization… read more here.
Keywords: bacterial phosphotransferase; dimerization; allosteric manner; autophosphorylation ... See more keywords
Dimerization of Proline Dehydrogenase from Thermus thermophilus Is Crucial for Its Thermostability.
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology journal"
DOI: 10.1002/biot.201800540
Abstract: Thermus thermophilus proline dehydrogenase ( TtProDH) catalyzes the first step in proline catabolism. The thermostable flavoenzyme consists of a distorted triosephosphate isomerase (TIM) barrel and three N-terminal helices: αA, αB, and αC. Using maltose-binding protein… read more here.
Keywords: proline dehydrogenase; dimerization; thermostability; thermus ... See more keywords
Engineering soluble artificial epidermal growth factor receptor mimics capable of spontaneous in vitro dimerization
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27659
Abstract: Epidermal growth factor receptor (EGFR) is a clinically validated target for a multitude of human cancers. The receptor is activated upon ligand binding through a critical dimerization step. Dimerization can be replicated in vitro by… read more here.
Keywords: dimerization; kinase; factor receptor; growth factor ... See more keywords
Synthesis of dibenzo[a,j]phenazine compounds using hemicucurbit[6]uril‐catalyzed oxidative dimerization of 2‐arylamines
Sign Up to like & getrecommendations! Published in 2020 at "ChemCatChem"
DOI: 10.1002/cctc.202000956
Abstract: A supramolecular catalytic strategy for the synthesis of dibenzo[a,j]phenazine compounds from 2‐arylamines is demonstrated. The dimerization is achieved through the catalytic action of HemiQ[6] in an acidic environment. Kinetic constants and activation energies have been… read more here.
Keywords: synthesis dibenzo; dibenzo phenazine; dimerization; phenazine compounds ... See more keywords
Electronic processes in NO dimerization on Ag and Cu clusters: DFT and MRMP2 studies
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Computational Chemistry"
DOI: 10.1002/jcc.25568
Abstract: Experimentally observed NO dimerization on Cu and Ag surfaces is surprising because binding energy of NO dimer is very small in gas phase. MRMP2, MP2 to MP4, CCSD(T), and DFT studies of NO dimerization on… read more here.
Keywords: order; energy; dimerization; cu2 ... See more keywords
Characterization of the role of Kunitz‐type protease inhibitor domain in dimerization of amyloid precursor protein
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Computational Chemistry"
DOI: 10.1002/jcc.27100
Abstract: A major difference between amyloid precursor protein (APP) isoforms (APP695 and APP751) is the existence of a Kunitz type protease inhibitor (KPI) domain which has a significant impact on the homo‐ and hetero‐dimerization of APP… read more here.
Keywords: amyloid precursor; domain; dimerization; precursor protein ... See more keywords
Dimerization of a ubiquitin variant leads to high affinity interactions with a ubiquitin interacting motif
Sign Up to like & getrecommendations! Published in 2019 at "Protein Science"
DOI: 10.1002/pro.3593
Abstract: We previously described structural and functional characterization of the first ubiquitin variant (UbV), UbV.v27.1, engineered by phage display to bind with high affinity to a specific ubiquitin interacting motif (UIM). We identified two substitutions relative… read more here.
Keywords: interacting motif; high affinity; affinity; dimerization ... See more keywords
Study of novel androgen receptor V770 variant in androgen insensitivity syndrome patients reveals the transitional state of the androgen receptor ligand binding domain homodimer
Sign Up to like & getrecommendations! Published in 2023 at "Protein Science"
DOI: 10.1002/pro.4599
Abstract: We report the discovery of the androgen receptor missense mutation V770D, that was found in two sisters suffering from complete androgen insensitivity. Experimental validation of AR V770 variants demonstrated that AR V770D was transcriptionally inactive… read more here.
Keywords: v770; lbd dimer; androgen receptor; dimerization ... See more keywords
Ultra-Highly Active Ni-Doped MOF-5 Heterogeneous Catalysts for Ethylene Dimerization.
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DOI: 10.1002/smll.202301235
Abstract: Here, an ultra-highly active Ni-MOF-5 catalyst with high Ni loading for ethylene dimerization is reported. The Ni-MOF-5 catalysts are synthesized by a facile one-pot co-precipitation method at room temperature, where Ni2+ replaces Zn2+ in MOF-5.… read more here.
Keywords: active doped; heterogeneous catalysts; ethylene dimerization; highly active ... See more keywords
Dimerization of Isobutene in C4 Mixtures in the Presence of Ethanol Over Acid Ion-Exchange Resin DH-2
Sign Up to like & getrecommendations! Published in 2019 at "Catalysis Letters"
DOI: 10.1007/s10562-019-02685-y
Abstract: Isobutene dimerization of C4 mixtures with the simulated components of industrial fluid catalytic cracking (FCC) gas stream was carried out in a fixed-bed microreactor over the acid ion-exchange resin (DH-2) in the presence of ethanol.… read more here.
Keywords: ion exchange; dimerization; presence ethanol; reaction ... See more keywords
smFRET study of rRNA dimerization at the peptidyl transfer center.
Sign Up to like & getrecommendations! Published in 2021 at "Biophysical chemistry"
DOI: 10.1016/j.bpc.2021.106657
Abstract: The ribosome is a ribozyme. At the peptidyl transfer center (PTC) of 180 nt, two loops (the A- and P- loops) bind to tRNAs and position them in close proximity for efficient peptidyl ligation. There is… read more here.
Keywords: dimerization; peptidyl; transfer center; peptidyl transfer ... See more keywords