TMED2 Potentiates Cellular IFN Responses to DNA Viruses by Reinforcing MITA Dimerization and Facilitating Its Trafficking.
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DOI: 10.1016/j.celrep.2018.11.048
Abstract: Mediator of IRF3 activation (MITA), also known as stimulator of interferon genes (STING), plays a vital role in the innate immune responses to cytosolic dsDNA. The trafficking of MITA from the ER to perinuclear vesicles is necessary… read more here.
Keywords: tmed2; dimerization facilitating; tmed2 potentiates; ifn responses ... See more keywords