Articles with "dimethoxy quinazolin" as a keyword



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6,7-Dimethoxy-quinazolin-4-yl-amino-thiophene-2-carboxamides as Potent Inhibitors of VEGF Receptors 1 and 2

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Published in 2017 at "Journal of Heterocyclic Chemistry"

DOI: 10.1002/jhet.2675

Abstract: The identification of agents with antiproliferative activity against endothelial cells has significant value for the treatment of many angiogenesis-dependent pathologies. The vascular endothelial growth factor (VEGF) and its receptors have been implicated as key factors… read more here.

Keywords: thiophene carboxamides; vegf receptors; dimethoxy quinazolin; quinazolin amino ... See more keywords
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6,7‐Dimethoxy‐Quinazolin‐4‐yl‐Amino‐Nicotinamide Derivatives as Potent Inhibitors of VEGF Receptor II

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Published in 2017 at "Journal of Heterocyclic Chemistry"

DOI: 10.1002/jhet.2750

Abstract: The sprouting of new blood vessels, or angiogenesis, is necessary for any solid tumor to grow large enough to cause life-threatening disease. Vascular endothelial growth factor (VEGF) is one of the key promoters of tumor-induced… read more here.

Keywords: quinazolin amino; vegf receptor; dimethoxy quinazolin;