First total synthesis of 7-(3,4-dimethoxyphenyl)-1-(4-hydroxy-3-methoxyphenyl)heptan-3-one (a diarylheptanoid).
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DOI: 10.1080/14786419.2025.2522812
Abstract: Herein, we demonstrate the first total synthesis of a natural product, 7-(3,4-dimethoxyphenyl)-1-(4-hydroxy-3-methoxyphenyl)heptan-3-one using the commercially available starting materials 1,2- dimethoxy benzene and vanillin with 20% overall yield in 15 steps. The present synthesis employs classical… read more here.
Keywords: dimethoxyphenyl hydroxy; methoxyphenyl heptan; hydroxy methoxyphenyl; synthesis ... See more keywords