Exploring the gem-dimethyl effect in the formation of imine-based macrocycles and cages
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DOI: 10.1039/c7nj02069d
Abstract: Using the gem-dimethyl effect as a platform, a variety of organic [2+2] macrocycles and [2+3] cofacial cages was obtained in high yields. Imine-based macrocyclization could be performed even at high concentrations (0.5 to 1.0 M),… read more here.
Keywords: imine based; dimethyl effect; gem dimethyl;