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Published in 2019 at "Amino Acids"
DOI: 10.1007/s00726-019-02737-y
Abstract: The importance of l-arginine (Arg) and relatives, including l-homoarginine (hArg) and asymmetric dimethylarginine (ADMA), in humans infected with Helicobacter pylori (Hp) is little understood. ADMA is produced by asymmetric dimethylation of the guanidine group of…
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Keywords:
citrullination;
arg;
dimethylation;
infection ... See more keywords
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Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c04648
Abstract: Characterization of protein arginine dimethylation presents significant challenges due to its occurrence at the substoichiometric level. To enable a targeted MS/MS analysis of these dimethylation sites, we developed the mNeuCode (methyl-neutron-coding) tag by metabolically labeling…
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Keywords:
targeted proteome;
dimethylation;
arginine dimethylation;
proteome analysis ... See more keywords
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Published in 2020 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.0c00116
Abstract: Protein arginine methylation regulates diverse biological processes including signaling, metabolism, splicing, and transcription. Despite its important biological roles, arginine dimethylation remains an understudied post-translational modification. Partly, this is because the two forms of arginine dimethylation,…
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Keywords:
arginine dimethylation;
dimethylation;
collision energy;
normalized collision ... See more keywords