Disruptions in hepatic glucose metabolism are involved in the diminished efficacy after chronic treatment with glucokinase activator
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DOI: 10.1371/journal.pone.0265761
Abstract: Glucokinase activators are regarded as potent candidates for diabetes treatment, however, in clinical studies on patients with type 2 diabetes, a diminishing efficacy was observed after chronic treatment with them. The mechanism of this reduction… read more here.
Keywords: chronic treatment; efficacy; glucokinase activator; diminished efficacy ... See more keywords