A diminished hydrophobic effect inside the GroEL/ES cavity contributes to protein substrate destabilization
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DOI: 10.1073/pnas.2213170119
Abstract: Significance Protein confinement in compartments is ubiquitous in biology. Here, we show that a protein encapsulated in the GroEL/ES chaperonin cage is strongly destabilized owing, at least in part, to a diminished hydrophobic effect. Hence,… read more here.
Keywords: cavity; hydrophobic effect; diminished hydrophobic; effect inside ... See more keywords